The effects of low impact aerobic exercise on acute phase proteins in older obese women with type П diabetes
Aim and Background: Several studies have shown that adipose tissue plays an important role to produce large amounts of inflammatory cytokines such as IL-6 and CRP by the development of insulin resistance, diabetes and metabolic syndrome. The aim of this study is investigation of the effect of low impact aerobic exercise on acute phase proteins (APPs) and lipid profile status in older obese women with type П diabetic. Methodology: Twenty diabetic old women (mean age 55.05, BMI=28.06 Kg/m2) from Izeh diabetic clinic with no specific disease were randomly assigned to two groups of training (3 times a week, 60 minutes per session), aerobic group (n=10) and control group (n=10) that blood samples were taken each of them. Then resting blood sampling and anthropometric factors were taken from anterior vein in 5cc amount, while they did not eat any breakfast for 8-hours. Experimental group were directed to the LIA exercise program such as musical aerobic exercise with 40-60 percent of maximum heart rate for 50 minutes, 3 sessions per week for 8 weeks. After 8 weeks blood samples, APPs, lipid profile and anthropometric measures were taken from two groups. Findings: 8 week Low impact aerobic exercise in diabetic old women caused a significant decrease in CRP concentrations (p=0.01) A slight but no significant decrease in serum IL-6 (p=0.85), fibrinogen (p=0.29), WBC (p=0.14), TG (p=0.26), LDL (p=0.12) and TC (p=0.63), also caused a slight but no significant increase in HDL (p=0.93) compared with the control group. Conclusion: Based on research results, probably more intense or over 8 weeks aerobic training could be effective on APPs levels and lipid profile in obese diabetic elderly women.
Keywords: Diabetes type П, Aerobic dance training, APPs and obese older women
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