• Musa Ibrahim Department of Human Physiology, Kogi state university, Anyigba, Nigeria
  • Mabrouk M.A Department of Human Physiology, Bayero University, Kano, Nigeria
  • Tanko Y Department of Human Physiology, Ahmadu Bello University, Zaria, Nigeria


Physical exercise decreases renal hemodynamics due to high demand of the skin and active muscle tissue. The aim of this study was to investigate the dynamics of renal function in male football players and to compare the values to that of the non-athletes of similar age. Employing purposeful sampling technique, 20 male football players and 20 non-athletes were recruited for this cross sectional study following inclusion and exclusion criteria. The university institutional review board (ABUTH/HREC/TRG/36) gave approval for all procedures in accordance with the Declaration of Helsinki. Blood samples were taken at rest, to measured serum creatinine and urea concentrations and to estimate glomerular filtration rate (eGFR). The independent students-t-test was used to compare values between the two groups. The level of significance was set at P< 0.05.  Our result showed that there was no significant differences (p>0.05) in the serum creatinine (70.052.3 mol/l vs 65.454.1 mol/l), urea (2.900.1 mmol/l vs 2.770.1 mmol/l) and eGFR ((123.715.06 ml/min/1.73m2 vs 114.548.88 ml/min/1.73m2) between the male football players and non athletes. The absence of significance changes in these parameters suggests that, high intensity and frequency of footballing, not enough to evoke clinical changes in renal function. This observation has implications for sports physiology.
Keywords: renal function, non athlete, performance status, football players


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1. Andersson, H., Raastad, T., Nilsson, J., Paulsen, G., Garthe, I., Kadi F. (2008). Neuromuscular Fatigue and Recovery in Elite Female Soccer: Effects of Active Recovery. Medicine and Science in Sports and Exercise, 40: 372-380.
2. Banfi G., Colombini A., Lombardi G., Lubkowska A. (2012). Metabolic markers in sports medicine. Adv Clin Chem, 56, 154.
3. Banfi G., Del Fabbro M., Lippi G. (2006). Relation between serum creatinine and body mass index in elite athletes of different sport disciplines. Br J Sports Med, 40(8), 6758.
4. Banfi G., Del Fabbro M., Lippi G. (2009). Serum creatinine concentration and creatinine-based estimation of glomerular filtration rate in athletes. Sports Med, 39(4), 3317.
5. Cazzola, R., Russo-Volpe, S., Cervato, G., and Cestaro, B, (2003). Biochemical Assessments of Oxidative Stress, Erythrocyte Membrane Fluidity and Antioxidant Status in Professional Soccer Players and Sedentary Controls. European Journal of Clinical Investigation 33, 924930
6. Dolci, A.; Nanni, G.; Sisca, G.; Costantino, B.; Baldari, A.; Palaia, G.; Banfi, G. (2003). Leukocyte counts in professional football players. Haematologica, 88(9) :ELT31,
7. Gorce-Dupuy A. M., Vela C., Badiou S., Sophie A., Christophe B., Nicolas J., Martine R., Franoise D., Marie M., Vernet H., Destizons D., and Cristol J.P (2012). Antioxidant and oligonutrient status, distribution of amino acids, muscle damage, inflammation, and evaluation of renal function in elite rugby players. Clin Chem Lab Med, 50, 177789.
8. Griffith, H.W. (2002). Guide to sports ?njuries. Birol Press Release Distribution and Trade Limited Company _stanbul. 6-7.
9. Lazarim F. L., Antunes-Neto J. M., da Silva F. O., Nunes LA, Bassini-Cameron A, Cameron LC, Alves AA, Brenzikofer R, de Macedo DV. (2009). The upper values of plasma creatine kinase of professional soccer players during the Brazilian National Championship. J Sci Med Sport, 12(1), 8590.
10. Levey A. S., Coresh J., Greene T., Stevens LA, Zhang YL, Hendriksen S, Kusek JW, Van Lente F; (2006). Chronic Kidney Disease Epidemiology Collaboration Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med, 145, 247 54.
11. Li Y, Zhu Y, Zhang J, Zhang X, Zeng Y, (2012). Biochemical changes and endocrine responses in precompetition training in elite swimmers. Biol Sport, 29:71-75.
12. Lin, Q.Q., Lin, R., Ji, Q.L., Zhang, J.Y., Wang, W.R., Yang, L.N.,and Zhang, KF.(2011). Effect of exercise training on renal function and renal aquaporin-2 expression in rats with chronic heart failure. Clinical and Experimental Pharmacology and Physiology, 38:179185.
13. Lippi G, Banfi G, Luca Salvagno G, Montagnana M, Franchini M, Cesare Guidi G. (2008). Comparison of creatinine-based estimations of glomerular filtration rate in endurance athletes at rest. Clin Chem Lab Med, 46, 2359.
14. Manzi V., DOttavio S., Impellizzeri F. M., Chaouachi, A, Chamari, K, and Castagna, C. (2010). Profile of weekly training load in elite male professional basketball players. J Strength Cond Res, 24(5), 1399406.
15. McLellan C. P., Lovell D. I., Gass G. C. (2011). Markers of postmatch fatigue in professional Rugby League players. J Strength Cond Res, 25(4), 10309.
16. Meeusen R, Duclos M, Foster C, Fry A, Gleeson M, Nieman D, Raglin J, Rietjens G, Steinacker J, Urhausen A; (2013). Prevention, diagnosis, and treatment of the overtraining syndrome: joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. Med Sci Sports Exerc, 45(1), 186205.
17. Mili? R., Banfi G., Del Fabbro M., Dopsaj.M. (2011). Serum creatinine concentrations in male and female elite swimmers. Correlation with body mass index and evaluation of estimated glomerular filtration rate. Clin Chem Lab Med, 49, 2859.
18. Nunes, L.A.S., and Macedo, D.V. (2008). Reference intervals for biochemical parameters in physically active young men. Clinical Chemistry and Laboratory Medicine,Vol.46 (Aug), pp.S1-S859, ISSN 1434-6621.
19. Perrone R D, Madias N E, Levey A S. (1992). Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem. 3819331953.1953
20. Popovic, S.; Akpinar, S.; Jaksic, D.; Matic, R. & Bjelica, D. (2013). Comparative study of anthropometric measurement and body composition between elite soccer and basketball players. Int. J. Morphol., 31(2):461-7.
21. Popovic, S.; Bjelica, D.; Jaksic, D. & Hadzic, R. (2014). Comparative study of anthropometric measurement and body composition between elite soccer and volleyball players. Int. J. Morphol., 32(1):267- 74.
22. Popovic, S.; Bjelica, D.; Petkovic, J. & Muratovic, A. (2012). Comparative Study of Anthropometric Measurement and Body Composition between Elite Soccer and Handball Players. 4th International Scientific Conference "Contemporary Kinesiology". Split, Faculty of Kinesiology, University of Split. pp.102-8.
23. Rustad, P., Felding, P., Franzson, L., Kairisto, V., Lahti, A., Mrtensson, A., Hyltoft Petersen, P., Simonsson, P., Steensland, H. & Uldall, A. (2004). The Nordic Reference Interval Project 2000: recommended reference intervals for 25 common biochemical properties. Scandinavian journal of clinical and laboratory investigation,Vol.64, No.4, pp.271-284, ISSN 0036 5513
24. Samir, Shereen, M. Mostafa, Abeer, F. (2013). Role of ghrelin in exhaustive exercise- induced oxidative stress in rat Brain and liver. International Journal of Applied Exercise Physiology, 2(1): 26-39.
25. Sirois, M. (1995). Blood biochemistry, In: Veterinary Clinical Pathology Laboratory.
26. Warburton, D. E. R., R.C. Welsh, M.J. Haykowsky, D.A. Taylor and D.P. Humen, (2002). Biochemical changes as a result of prolonged strenuous exercise. British Journal of Sports Medicine, 36: 301-303.
27. Wybenga, R. Di Giorgio, J., and Pileggi. V. J. (1971). Manual and automated methods for urea nitrogen measurement in whole serum. Clinical Chemistry, 17: 891-895.
How to Cite
Ibrahim, M., M.A, M., & Y, T. (2016). RENAL FUNCTION TEST PARAMETERS IN MALE FOOTBALL PLAYERS. International Journal of Applied Exercise Physiology, 5(2), 20-26.
Applied Exercise Physiology