the Effect of six weeks of high intensity interval training and zinc supplement on serum creatine kinase and uric acid levels in futsal players
HIT and Zinc on CK and UA
Background: strenuous training-induced reactive oxygen species is associated with several chronic diseases by damaging cell proteins and membrane lipids; it seems uric acid as a major intracellular antioxidant could lower membranous lipid peroxidation and muscle damage. The aim of this study was to examine the effect of six weeks of high-intensity interval training with and without zinc on serum Creatine Kinase and uric acid in female futsal players.
Methods: Thirty-two female futsal players were randomly divided into four groups: placebo, Zinc, HIT and Zinc+HIT. All subjects had to attend futsal-specific training three sessions per week. Zinc and Placebo groups took 30 mg day−1 of zinc gluconate or dextrose, respectively; HIT groups accomplished high-intensity interval training contained 6 to 10 repetitions of a 30-second running at 100% of VO2peak with a 4-minutes rest between efforts, during six weeks.
Results: After six weeks, Creatine Kinase levels augmented insignificantly from 83.98 to 120.19 (P=0.101) in placebo, from 99.58 to 150.1(P=0.167) in HIT and from 81.07 to 107.90 (P=0.152) in HIT+Zinc group; while Creatine Kinase levels increased significantly from 66.86 to 124.81(P=0.004) only in Zinc group. Uric acid levels increased in all groups (Placebo (P=1), Zinc (P=0.317), HIT (P=0.157), Zinc+HIT (P=1)) insignificantly
Conclusions: The findings indicated that after six weeks, serum Creatine Kinase and uric acid levels increased insignificantly in all groups; Creatine Kinase levels augmented significantly, only in Zinc group. Zinc as an antioxidant supplement could not decrease the muscle damage, and even increased the serum Creatine Kinase as a marker of muscle damage, significantly
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